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Bioactivity:
SX-517 is a potent noncompetitive boronic acid CXCR1/2 antagonist. SX-517 inhibits CXCL1-induced Ca(2+) flux (IC50 = 38 nM) in human PMNs.
CAS nr:
1240494-13-6
Purity:
98%
Molecular Weight:
382,22
SMILES:
OB(C1=CC=CC=C1CSC2=NC=C(C(NC3=CC=C(F)C=C3)=O)C=C2)O
Formula:
C19H16BFN2O3S
Pathway:
Target: