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Bioactivity:
Refametinib (RDEA119, Bay 86-9766) is an effective, ATP non-competitive and specific inhibitor of MEK1/2 (IC50: 19/47 nM).
CAS nr:
923032-37-5
Purity:
98%
Molecular Weight:
572,34
SMILES:
Fc1cc(OC)c(NS(=O)(=O)C2(CC2)C[C@H](O)CO)c(Nc2ccc(I)cc2F)c1F
Formula:
C19H20F3IN2O5S
Pathway:
MAPK
Target:
MEK