Bioactivity:

MK-0674 is an effective and selective cathepsin K inhibitor (IC50: 0.4 nM). It also displays 1156, 1465, 11857, and 243 fold selectivity over Cat B, Cat F, Cat L, and Cat S.

CAS nr:

887781-62-6

Purity:

98%

Molecular Weight:

527,5

SMILES:

N#CC1(CC1)NC([C@H](CC(C)(C)F)N[C@@H](C2=CC=C(C3=CC=C(C=C3)[C@@H](O)C(F)F)C=C2)C(F)(F)F)=O

Formula:

C26H27F6N3O2

Pathway:

Apoptosis

Target:

BCL