SHP099 T3564
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Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
SHP099 free base is an effective, selective, orally bioavailable, and efficacious SHP2 inhibitor (IC50 =0.07 _M and p-ERK modulation in cells IC50 = 0.250 _M). SHP099 shows dose-dependent pathway inhibition and antitumor activity in xenograft models.
CAS nr:
1801747-42-1
Purity:
98%
Molecular Weight:
352,26
SMILES:
NC1=NC(N2CCC(C)(N)CC2)=CN=C1C3=CC=CC(Cl)=C3Cl
Formula:
C16H19Cl2N5
Pathway:
Metabolism,Apoptosis
Target:
Phosphatase,PERK