Abexinostat T0431
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
PCI-24781 (Abexinostat) is a new pan-HDAC inhibitor mainly targeting HDAC1 (Ki: 7 nM), also have moderate inhibitory for HDACs 2, 3, 6, and 10 and greater than 40-fold selectivity against HDAC8. Phase 1/2.
CAS nr:
783355-60-2
Purity:
98%
Molecular Weight:
397,42
SMILES:
CN(Cc1c(C(=O)NCCOc2ccc(C(=O)NO)cc2)oc2c1cccc2)C
Formula:
C21H23N3O5
Pathway:
DNA Damage/DNA Repair,Chromatin/Epigenetic
Target:
HDAC,HDAC
