Bioactivity:

Fasudil Hydrochloride is a potent inhibitor of ROCK1, PKA, PKC, and MLCK with Ki of 0.33 _M, 1.0 _M, 9.3 _M and 55 _M, respectively.

CAS nr:

105628-07-7

Purity:

98%

Molecular Weight:

327,83

SMILES:

C1CNCCN(C1)S(=O)(=O)c1cccc2c1ccnc2.Cl

Formula:

C14H18ClN3O2S

Pathway:

Cytoskeletal Signaling,Chromatin/Epigenetic,Metabolism,Cell Cycle/Checkpoint,Microbiology/Virology,Tyrosine Kinase/Adaptors,Proteases/Proteasome,Autophagy,Stem Cells,Cytoskeletal Signaling,Cell Cycle/Checkpoint,Metabolism,Membrane transporter/Ion channel

Target:

PKC,PKC,Serine/threonin kinase,Serine/threonin kinase,HIV Protease,PKA,HIV Protease,Autophagy,ROCK,ROCK,ROCK,Calcium Channel,Calcium Channel