Bioactivity:

Polmacoxib is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through inhibiting tumor cell proliferation.

CAS nr:

301692-76-2

Purity:

98%

Molecular Weight:

361,39

SMILES:

CC1(C(=O)C(=C(O1)C2=CC=C(C=C2)S(=O)(=O)N)C3=CC(=CC=C3)F)C

Formula:

C18H16FNO4S

Pathway:

Metabolism,Neuroscience,Immunology/Inflammation

Target:

Carbonic Anhydrase,COX,COX