Bioactivity:

EXP-3174 is a potent AT1 antagonist (Kis: 0.57 nM, rat; 0.67 nM, human), producing a depressor response and vasodilatation. EXP3174, a metabolite of losartan, is more potent than losartan in blocking the angiotensin II-induced responses in vascular smooth

CAS nr:

124750-92-1

Purity:

98%

Molecular Weight:

436,9

SMILES:

c1(n(c(c(n1)Cl)C(=O)O)Cc1ccc(cc1)c1c(cccc1)c1n[nH]nn1)CCCC

Formula:

C22H21ClN6O2

Pathway:

Endocrinology/Hormones

Target:

RAAS