Bioactivity:

PROTAC Mcl1 degrader-1 induces the ubiquitination and proteasomal degradation of Mcl-1 by introducing the E3 ligase cereblon (CRBN)-binding ligand pomalidomide to Mcl-1 inhibitor S1-6 with _M-range affinity.�PROTAC Mcl1 degrader-1, a proteolysis targeting

CAS nr:

2163793-38-0

Purity:

98%

Molecular Weight:

909,84

SMILES:

O=C(C1=CC=CC(NCCCCCCNC(CCCCC(NCCN2C(C3=C4C(C2=O)=CC=C(C4=CC=C3)SC5=CC=C(C=C5)Br)=O)=O)=O)=C1C6=O)N6C7CCC(NC7=O)=O

Formula:

C45H45BrN6O8S

Pathway:

Apoptosis

Target:

BCL