Bioactivity:

CHMFL-BTK-01 is an irreversible inhibitor of BTK (IC50: 7 nM) and also potently inhibits BTK Y223 auto-phosphorylation.

CAS nr:

2095280-64-9

Purity:

98%

Molecular Weight:

647,76

SMILES:

O=C(NC1=CC=CC(C(C=C2NC3=CC=C(C(N4CCOCC4)=O)C(NC(C=C)=O)=C3)=CN(C)C2=O)=C1C)C5=CC=C(C(C)(C)C)C=C5

Formula:

C38H41N5O5

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors

Target:

BTK,BTK