Bioactivity:

PLX8394 is an orally active inhibitor of serine/threonine-protein kinase B-Raf (BRAF) protein. PLX8394 can selectively bind to and inhibit the activity of both wild-type and mutated forms of BRAF, then inhibit the proliferation of tumor cells which expres

CAS nr:

1393466-87-9

Purity:

98%

Molecular Weight:

542,54

SMILES:

F[C@@H]1CCN(C1)S(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(cc23)-c2cnc(nc2)C2CC2)c1F

Formula:

C25H21F3N6O3S

Pathway:

MAPK

Target:

Raf