Bioactivity:

Naproxen is a COX-1 and COX-2 inhibitor (IC50s: 8.72 and 5.15 _M, respectively in cell assay). Naproxen etemesil is a lipophilic and non-acidic prodrug of naproxen. It is hydrolyzed to pharmacologically active Naproxen once absorbed.

CAS nr:

385800-16-8

Purity:

98%

Molecular Weight:

336,4

SMILES:

O=C(OCCS(C)(=O)=O)[C@@H](C)C1=CC2=CC=C(OC)C=C2C=C1

Formula:

C17H20O5S

Pathway:

Metabolism

Target:

PDE