Bioactivity:

Dasatinib hydrochloride is a highly ATP competitive, potent, orally active inhibitor of dual Src/Bcr-Abl(with Ki values of 16 pM and 30 pM for Src and Bcr-Abl, respectively), and has potent antitumor activity.

CAS nr:

854001-07-3

Purity:

98%

Molecular Weight:

524,47

SMILES:

Cl.CC1=NC(=CC(=N1)NC2=NC=C(S2)C(=O)NC3=C(C)C=CC=C3Cl)N4CCN(CCO)CC4

Formula:

C22H27Cl2N7O2S

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors,Cytoskeletal Signaling,Tyrosine Kinase/Adaptors,Angiogenesis,Tyrosine Kinase/Adaptors

Target:

Bcr-Abl,Bcr-Abl,Bcr-Abl,Src,Src,c-Kit