Bioactivity:

DHODH-IN-8 has antimalarial activity. DHODH-IN-8 is an inhibitor of human and Plasmodium falciparum dihydroorotate dehydrogenase (DHODH) with IC50 of 0.13 _M and 47.4 _M, and Kis of 0.016 _M and 5.6 _M, respectively.

CAS nr:

1148126-03-7

Purity:

98%

Molecular Weight:

312,75

SMILES:

C/C(O)=C(C#N)/C(NC1=CC=C(C2=CC=CC=C2Cl)C=C1)=O

Formula:

C17H13ClN2O2

Pathway:

Metabolism

Target:

Dehydrogenase