Bioactivity:

Ribociclib hydrochloride is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively). It is over 1,000-fold less potent against the cyclin B/CDK1 complex.

CAS nr:

1211443-80-9

Purity:

98%

Molecular Weight:

471

SMILES:

O=C(N(C)C)C(N1C2CCCC2)=CC(C1=N3)=CN=C3NC(N=C4)=CC=C4N5CCNCC5.Cl

Formula:

C23H31ClN8O

Pathway:

Cell Cycle/Checkpoint

Target:

CDK