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TargetMol Chemicals

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TargetMol Chemicals Inc. specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.

TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, their lab allows them to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of their clients.

With TargetMol’s high-quality products & services, fast & efficient global supply chain and professional technical support, TargetMol believes they will help you shorten your research process and yield a more successful result.

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Dacomitinib T2483

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Specifications

1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

Dacomitinib(PF299804; PF-00299804) is a highly selective, orally bioavailable small-molecule inhibitor of the HER family of tyrosine kinases with IC50 of 6, 45.7 and 73.7 nM for EGFR, ERBB2, and ERBB4, respectively.

CAS nr:

1110813-31-4

Purity:

98%

Molecular Weight:

469,94

SMILES:

O=C(Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC)/C=C/CN1CCCCC1

Formula:

C24H25ClFN5O2

Pathway:

JAK/STAT signaling,Tyrosine Kinase/Adaptors,Angiogenesis,Apoptosis

Target:

EGFR,EGFR,EGFR,Apoptosis