Bioactivity:

SU16f is a potent and selective PDGFR_ inhibitor (IC50s: 10 nM, 140 nM, 2.29 _M for PDGFR_, PDGFR1, PDGFR2, respectively). Neutralization of PDGFR_ receptor by SU16f blocks the promoting role of GC-MSCs conditioned medium in gastric cancer cell proliferat

CAS nr:

251356-45-3

Purity:

98%

Molecular Weight:

386,44

SMILES:

O=C(O)CCC1=C(C)NC(/C=C2C(NC3=C\2C=CC(C4=CC=CC=C4)=C3)=O)=C1C

Formula:

C24H22N2O3

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors

Target:

PDGFR,PDGFR