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Bioactivity:
MLN4924 is an effective and specific small molecule NEDD8-activating enzyme (NAE) inhibitor (IC50: 4.7 nM).
CAS nr:
905579-51-3
Purity:
98%
Molecular Weight:
443,52
SMILES:
NS(=O)(=O)OC[C@@H]1C[C@H](C[C@@H]1O)n1ccc2c(N[C@H]3CCc4ccccc34)ncnc12
Formula:
C21H25N5O4S
Pathway:
Metabolism,Ubiquitination
Target:
NEDD8,E1/E2/E3 Enzyme