Bioactivity:

AC710 Mesylate is a potent PDGFR inhibitor (Kds: 0.6, 1.57, 1, 1.3, 1.0 nM for FLT3, CSF1R, KIT, PDGFR_ and PDGFR_).

CAS nr:

1351522-05-8

Purity:

98%

Molecular Weight:

658,81

SMILES:

O=C(C1=NC=C(OC2CC(C)(C)N(CC)C(C)(C)C2)C=C1)NC3=CC=C(NC(NC4=NOC(C(C)(C)C)=C4)=O)C=C3.CS(=O)(O)=O

Formula:

C32H46N6O7S

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors

Target:

PDGFR,PDGFR