GNE-493 T7166
Specifications
| 1mg/5mg/10mg/25mg/50mg/100mg |
Bioactivity:
GNE-493 is potent, selective, and orally available PI3K and mTOR inhibitor with potential anticancer activity.IC50s of 3.4 nM, 12 nM, 16 nM, 16 nM and 32 nM for PI3K_, PI3K_, PI3K_, PI3K_ and mTOR,respectively.
CAS nr:
1033735-94-2
Purity:
98%
Molecular Weight:
372,44
SMILES:
CC(C)(O)c1cc2nc(nc(N3CCOCC3)c2s1)-c1cnc(N)nc1
Formula:
C17H20N6O2S
Pathway:
PI3K/Akt/mTOR signaling,PI3K/Akt/mTOR signaling
Target:
mTOR,PI3K
