Bioactivity:

GSK J4 is an ethyl ester derivative of GSK J1, which is a potent JMJD3 inhibitor (IC50: 60 nM) with restricted cellular permeability due to the highly polar carboxylate group, and rapidly hydrolyzed by macrophage esterase upon administration leading to th

CAS nr:

T22819

Purity:

98%

Molecular Weight:

453,96

SMILES:

CCOC(=O)CCNC1=NC(=NC(=C1)N2CCC3=CC=CC=C3CC2)C4=CC=CC=N4.Cl

Formula:

C24H27N5O2�HCl

Pathway:

Others

Target:

Others