Bioactivity:

VZ185 is an effective and selective dual BRD7/9 PROTAC degrader (DC50s: 4.5 and 1.8 nM, respectively).

CAS nr:

2306193-61-1

Purity:

98%

Molecular Weight:

995,21

SMILES:

O=C([C@H]1N(C([C@@H](NC(C2(F)CC2)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC3=CC=C(C4=C(C)N=CS4)C=C3OCCCCCN5CCN(CC6=C(OC)C=C(C(C7=CC=NC=C87)=CN(C)C8=O)C=C6OC)CC5

Formula:

C53H67FN8O8S

Pathway:

Chromatin/Epigenetic

Target:

Epigenetic Reader Domain