Bioactivity:

Spebrutinib besylate (AVL-292 benzenesulfonate; CC-292 besylate) is a Btk kinase activity inhibitor (IC50<0.5 nM, Kinact/Ki=7.69_104 M-1s-1s).

CAS nr:

1360053-81-1

Purity:

98%

Molecular Weight:

581,62

SMILES:

COCCOC1=CC=C(NC2=NC=C(F)C(NC3=CC=CC(NC(C=C)=O)=C3)=N2)C=C1.O=S(C4=CC=CC=C4)(O)=O

Formula:

C28H28FN5O6S

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors

Target:

BTK,BTK