Bioactivity:

Vps34-IN1 is a potent and highly selective Vps34 inhibitor with IC50 of 25 nM invitro, which does not significantly inhibit the isoforms of class I as well as class II PI3Ks.

CAS nr:

1383716-33-3

Purity:

98%

Molecular Weight:

425,91

SMILES:

CC(C)(O)CNc1ncc(c(CC2CC2)n1)-c1ccnc(Nc2ccnc(Cl)c2)n1

Formula:

C21H24ClN7O

Pathway:

PI3K/Akt/mTOR signaling,Autophagy

Target:

PI3K,Autophagy