Bioactivity:

Chetomin is an inhibitor of HIF-1 by weaken transcription of HIF-1, disrupting the binding of HIF-1_ and HIF-2_ to p300 at low nanomolar concentrations.

CAS nr:

1403-36-7

Purity:

98%

Molecular Weight:

710,87

SMILES:

CN1C(=O)[C@@]23C[C@]4([C@H](Nc5ccccc45)N2C(=O)[C@]1(CO)SS3)n1cc(C[C@]23SS[C@](CO)(N(C)C2=O)C(=O)N3C)c2ccccc12

Formula:

C31H30N6O6S4

Pathway:

Cytoskeletal Signaling,Metabolism,Apoptosis,Angiogenesis,Chromatin/Epigenetic

Target:

HSP,HSP,Apoptosis,HIF,HIF