Bioactivity:

UK-370106 is a potent and highly selective inhibitor of MMP-3 with IC50 of 23 nM and MMP-12 with IC50 of 42 nM, and potently inhibits cleavage of [3H]-fibronectin by MMP-3 (IC50: 320 nM).

CAS nr:

230961-21-4

Purity:

98%

Molecular Weight:

572,73

SMILES:

CC1=C(C2=CC=CC=C2)C=CC(CCC[C@H](CC(O)=O)C(N[C@@H](C(C)(C)C)C(N[C@@H](C3=CC=CC=C3)COC)=O)=O)=C1

Formula:

C35H44N2O5

Pathway:

Proteases/Proteasome

Target:

MMP