Bioactivity:

PD153035 hydrochloride (ZM 252868; AG 1517) is a effective and selective inhibitor of EGFR (Ki: 5.2 pM, IC50: 29 pM); few influence against FGFR, PGDFR, InsR, CSF-1, and Src.

CAS nr:

183322-45-4

Purity:

98%

Molecular Weight:

396,67

SMILES:

Cl.COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OC

Formula:

C16H15BrClN3O2

Pathway:

Tyrosine Kinase/Adaptors,Angiogenesis,JAK/STAT signaling

Target:

EGFR,EGFR,EGFR