Bioactivity:

AZ9482 is a selective and potent inhibitor of PARP featuring an amide linkage to a 2-piperazinyl-3-cyano-pyridine. AZ9482 exhibits very potent activity of centrosome declustering with EC50 of < 18 nM in HeLa cells.

CAS nr:

1825345-33-2

Purity:

98%

Molecular Weight:

450,5

SMILES:

O=C1NN=C(CC2=CC=CC(C(N3CCN(C4=NC=CC=C4C#N)CC3)=O)=C2)C5=CC=CC=C51

Formula:

C26H22N6O2

Pathway:

DNA Damage/DNA Repair,Chromatin/Epigenetic

Target:

PARP,PARP