Bioactivity:

BPR1K871 is a potent and selective dual FLT3/AURKA inhibitor (IC50s: 22 nM and 19 nM for AURKA and FLT3) used as a preclinical development candidate for anti-cancer therapy.

CAS nr:

T10592

Purity:

98%

Molecular Weight:

526,05

SMILES:

O=C(NC1=CC(Cl)=CC=C1)NC2=NC=C(S2)CCNC3=NC=NC4=C3C=CC(OCCCN(C)C)=C4

Formula:

C25H28ClN7O2S

Pathway:

Angiogenesis,Tyrosine Kinase/Adaptors

Target:

FLT,FLT