Bioactivity:

SIS17 is a potent and selective HDAC 11 inhibitor with an IC50 value of 0.83 _M. SIS17, is active in cells and inhibited the demyristoylation of a known HDAC11 substrate, serine hydroxymethyl transferase 2, without inhibiting other HDACs.

CAS nr:

2374313-54-7

Purity:

98%

Molecular Weight:

366,6

SMILES:

CCCCCCCCCCCCCCCCNNC(=O)c1cccs1

Formula:

C21H38N2OS

Pathway:

DNA Damage/DNA Repair,Chromatin/Epigenetic

Target:

HDAC,HDAC