Bioactivity:

Tie2 kinase inhibitor, an optimized compound of SB-203580, is selective to Tie2 with IC50 of 0.25 _M, which is 200-fold more effective than p38.

CAS nr:

948557-43-5

Purity:

98%

Molecular Weight:

439,53

SMILES:

COc1ccc2cc(ccc2c1)-c1[nH]c(nc1-c1ccncc1)-c1ccc(cc1)S(C)=O

Formula:

C26H21N3O2S

Pathway:

Tyrosine Kinase/Adaptors

Target:

Tie-2