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(R)-(-)-Gossypol acetic acid T6396

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Specifications

size	1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

AT101, the R-(-) enantiomer of Gossypol acetic acid, binds with Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.32 _M, 0.48 _M and 0.18 _M; does not inhibit BIR3 domain and BID. Phase 2.

CAS nr:

866541-93-7

Purity:

98%

Molecular Weight:

578,61

SMILES:

CC(O)=O.CC(C)c1c(O)c(O)c(C=O)c2c(O)c(c(C)cc12)-c1c(C)cc2c(C(C)C)c(O)c(O)c(C=O)c2c1O

Formula:

C30H30O8�C2H4O2

Pathway:

Apoptosis,Autophagy

Target:

BCL,Autophagy