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Bioactivity:
Falnidamol (BIBX 1382) is a selective and orally active inhibitor of EGFR tyrosine kinase (IC50: 3 nM).
CAS nr:
196612-93-8
Purity:
98%
Molecular Weight:
387,84
SMILES:
CN1CCC(NC2=NC=C3C(C(NC4=CC(Cl)=C(F)C=C4)=NC=N3)=N2)CC1
Formula:
C18H19ClFN7
Pathway:
Tyrosine Kinase/Adaptors,Angiogenesis,JAK/STAT signaling
Target:
EGFR,EGFR,EGFR