Bioactivity:

Quarfloxin is a fluoroquinolone derivative with antineoplastic activity with IC50 values in the nanomolar range in neuroblastoma cells. Quarfloxin disrupts the interaction between the nucleolin protein and a G-quadruplex DNA structure in the ribosomal DNA

CAS nr:

865311-47-3

Purity:

98%

Molecular Weight:

604,67

SMILES:

CN1C(CCN=C(C(C(c2cc(F)c3N(CC4)CC4c4nccnc4)=O)=CN4c2c3Oc2cc3ccccc3cc24)O)CCC1

Formula:

C35H33FN6O3

Pathway:

DNA Damage/DNA Repair,Cell Cycle/Checkpoint

Target:

DNA/RNA Synthesis,DNA/RNA Synthesis