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Bioactivity:
AZ-3 is a potent and selective JAK1 inhibitor (IC50: 34 nM).
CAS nr:
2228908-91-4
Purity:
98%
Molecular Weight:
385,48
SMILES:
FC1=NC=C(N2C[C@H]3N(C)C[C@@H]2C3)C=C1NC4=NC(N[C@@H](CC)C)=C(C)C=N4
Formula:
C20H28FN7
Pathway:
JAK/STAT signaling,Chromatin/Epigenetic,Stem Cells,Angiogenesis
Target:
JAK,JAK,JAK,JAK