Bioactivity:

MLN2238 suppresses the chymotrypsin-like proteolytic (_5) site of the 20S proteasome(Ki50=0.93 nM, IC50=3.4 nM/). The biologically active form of MLN9708 is MLN2238 in aqueous solutions or plasma.

CAS nr:

1201902-80-8

Purity:

98%

Molecular Weight:

517,12

SMILES:

ClC1=C(C(NCC(N[C@@H](CC(C)C)B2OC(CC(O)=O)(C(O)=O)CC(O2)=O)=O)=O)C=C(Cl)C=C1

Formula:

C20H23BCl2N2O9

Pathway:

Proteases/Proteasome,Ubiquitination

Target:

Proteasome,Proteasome