Bioactivity:

Tenovin-6 Hydrochloride is an SIRT1, SIRT2 and HDAC8 inhibitor(IC50s of 21 _M, 10 _M, and 67 _M for SirT1, SirT2, and SirT3, respectively), and is also a potent p53 activator .

CAS nr:

1011301-29-3

Purity:

98%

Molecular Weight:

491,09

SMILES:

Cl.CN(C)CCCCC(=O)NC1=CC=C(NC(=S)NC(=O)C2=CC=C(C=C2)C(C)(C)C)C=C1

Formula:

C25H35ClN4O2S

Pathway:

DNA Damage/DNA Repair,Chromatin/Epigenetic,Autophagy,Metabolism,Apoptosis,DNA Damage/DNA Repair,Chromatin/Epigenetic

Target:

HDAC,HDAC,Autophagy,Dehydrogenase,p53,Sirtuin,Sirtuin