Bioactivity:

FTI 277 hydrochloride is an effective and specific farnesyltransferase (FTase) inhibitor (IC50: 500 pM); this selectivity is about 100-fold than the closely related GGTase I.

CAS nr:

180977-34-8

Purity:

98%

Molecular Weight:

484,07

SMILES:

COC(=O)[C@H](CCSC)NC(=O)c1c(cc(cc1)NC[C@H](CS)N)c1ccccc1.Cl

Formula:

C22H30ClN3O3S2

Pathway:

Metabolism,GPCR/G Protein,MAPK,Apoptosis

Target:

Transferase,Ras,Ras,Apoptosis