Bioactivity:

VU0467154 is a positive allosteric modulator of the M4 muscarinic acetylcholine receptor. The response to ACh with pEC50s of 7.75, 6.2, and 6 for a rat, human, and cynomolgus monkey M4 receptor, respectively.

CAS nr:

1451993-15-9

Purity:

98%

Molecular Weight:

444,45

SMILES:

O=C(C1=C(N)C2=C(C)C(C)=NN=C2S1)NCC3=CC=C(S(=O)(C(F)(F)F)=O)C=C3

Formula:

C17H15F3N4O3S2

Pathway:

Neuroscience

Target:

AChR