Bioactivity:

S-(+)-Rolipram inhibits human monocyte cyclic AMP-specific PDE4 with IC50 of 0.75 _M, has anti-inflammatory and anti-depressant activity in the central nervous system, less potent than its R enantiomer.

CAS nr:

85416-73-5

Purity:

98%

Molecular Weight:

275,34

SMILES:

COC1=C(OC2CCCC2)C=C(C=C1)[C@H]1CNC(=O)C1

Formula:

C16H21NO3

Pathway:

Apoptosis,Metabolism

Target:

Apoptosis,PDE