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TargetMol Chemicals

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TargetMol Chemicals Inc. specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.

TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, their lab allows them to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of their clients.

With TargetMol’s high-quality products & services, fast & efficient global supply chain and professional technical support, TargetMol believes they will help you shorten your research process and yield a more successful result.

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AKI603 T001-00000005

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Specifications

1mg/5mg/10mg/25mg/50mg/100mg

Bioactivity:

AKI603 is a novel small molecule inhibitor of Aurora kinase A (AurA)(IC50 = 12.3 nM). AKI603 is developed to overcome resistance mediated by BCR-ABL-T315I mutation. AKI603 exhibits strong anti-proliferative activity in leukemic cells[1][2].

CAS nr:

1432515-73-5

Purity:

98%

Molecular Weight:

409,45

SMILES:

O=[N+](C1=CC=C(NC2=NC(N3CCN(C)CC3)=CC(NC4=NNC(C)=C4)=N2)C=C1)[O-]

Formula:

C19H23N9O2

Pathway:

Chromatin/Epigenetic,Cell Cycle/Checkpoint

Target:

Aurora Kinase,Aurora Kinase