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Bioactivity:
AHU-377 is a potent NEP inhibitor with an IC50 of 5 nM. AHU-377 is a component of the heart failure medicine LCZ696.
CAS nr:
149709-62-6
Purity:
98%
Molecular Weight:
411,49
SMILES:
CCOC(=O)[C@H](C)C[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)CCC(O)=O
Formula:
C24H29NO5
Pathway:
Metabolism
Target:
Neprilysin