Bioactivity:

Abemaciclib Metabolites M2 is a metabolite of abemaciclib, acts as a potent CDK4 and CDK6 inhibitor (IC50s: 1-3 nM) with anti-cancer activity.

CAS nr:

1231930-57-6

Purity:

98%

Molecular Weight:

478,54

SMILES:

CC(N1C2=CC(C3=NC(NC4=NC=C(CN5CCNCC5)C=C4)=NC=C3F)=CC(F)=C2N=C1C)C

Formula:

C25H28F2N8

Pathway:

Cell Cycle/Checkpoint

Target:

CDK