Bioactivity:

BRD4 degrader AT1 is a highly selective Brd4 degrader based on PROTAC technology, with a Kd of 44 nM for Brd4BD2 in cells.

CAS nr:

2098836-45-2

Purity:

98%

Molecular Weight:

972,68

SMILES:

CC1=C(SC2=C1C(=N[C@H](C3=NN=C(N32)C)CC(=O)NCCCCCCSC(C)(C)[C@@H](C(=O)N4C[C@@H](C[C@H]4C(=O)NCC5=CC=C(C=C5)C6=C(N=CS6)C)O)NC(=O)C)C7=CC=C(C=C7)Cl)C

Formula:

C48H58ClN9O5S3

Pathway:

Chromatin/Epigenetic

Target:

Epigenetic Reader Domain