Bioactivity:

T025 is a highly potent and orally available inhibitor of Cdc2-like kinase (CLK)(Kds of 4.8, 0.096, 6.5, and 0.61 nM for CLK1, CLK2, CLK3, and CLK4, respectively).

CAS nr:

2407433-00-3

Purity:

98%

Molecular Weight:

382,42

SMILES:

CNC1=NC(NCC2=NC=CC=N2)=C(C(C3=CC=C(N=CC=C4)C4=C3)=CN5)C5=N1

Formula:

C21H18N8

Pathway:

Cell Cycle/Checkpoint

Target:

CDK