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Bioactivity:
LEE011 is an orally available, and highly specific CDK4/6 inhibitor (IC50_10/39 nM).
CAS nr:
1211441-98-3
Purity:
98%
Molecular Weight:
434,54
SMILES:
CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCNCC3)nc2n1C1CCCC1
Formula:
C23H30N8O
Pathway:
Cell Cycle/Checkpoint,Tyrosine Kinase/Adaptors,Angiogenesis
Target:
CDK,VEGFR,VEGFR