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Bioactivity:
MELK-IN-1 is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK),(IC50:3nm;Ki:0.39 nM).
CAS nr:
2095596-44-2
Purity:
98%
Molecular Weight:
539,62
SMILES:
O=C(C1=CC2=C(NC(/C2=C(NC3=CC=C(N(C)C(CN4CCN(C)CC4)=O)C=C3)/C5=CC=CC=C5)=O)C=C1)OC
Formula:
C31H33N5O4
Pathway:
PI3K/Akt/mTOR signaling
Target:
MELK