Bioactivity:

JTE-952 is a oral, potent active and selective Type II inhibitor of colony stimulating factor-1 receptor (CSF-1R or cFMS, type III receptor tyrosine kinase), with IC50 values of 13 nM and 261 nM for CSF1R and TrkA , respectively. Effective against a mouse

CAS nr:

1255303-54-8

Purity:

98%

Molecular Weight:

518,6

SMILES:

O=C(N1CC(C2=CC=C(OCC3=CC=C(C4CC4)C=C3)C(OC)=C2)C1)C5=NC=CC(COC[C@@H](O)CO)=C5

Formula:

C30H34N2O6

Pathway:

Immunology/Inflammation,Neuroscience,GPCR/G Protein

Target:

Histamine Receptor,Histamine Receptor,Histamine Receptor