Bioactivity:

GSK256066 is a selective PDE4B(equal affinity to isoforms A-D) inhibitor with IC50 of 3.2 pM, >380, 000-fold selectivity versus PDE1/2/3/5/6 and >2500-fold selectivity against PDE4B versus PDE7.Phase 2.

CAS nr:

801312-28-7

Purity:

98%

Molecular Weight:

518,58

SMILES:

CC1=C2C(=CC(=C1)S(=O)(=O)C3=CC=CC(=C3)C(=O)N(C)C)C(=C(C=N2)C(=O)N)NC4=CC(=CC=C4)OC

Formula:

C27H26N4O5S

Pathway:

Metabolism

Target:

PDE