Bioactivity:

RIPK1-IN-4 is a potent and selective type II kinase receptor interacting protein 1 (RIP1) kinase inhibitor and binds to a DLG-out inactive form of RIP1 (IC50s of 16 nM and 10 nM for RIP1 and ADP-Glo kinase).

CAS nr:

1481641-08-0

Purity:

98%

Molecular Weight:

401,46

SMILES:

CC(C)(C1=CC(NC(NC2=CC=C(C3=CC=CC4=C3C=CN=C4N)C=C2)=O)=NO1)C

Formula:

C23H23N5O2

Pathway:

Apoptosis

Target:

TNF